Edorium Journal of

Occupational and Environmental Medicine

 
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Review Article
 
Research applications of a coordination ability test system (CATSYS) during 30 years
John Heebøll1, Per Grove Thomsen2, Finn Gyntelberg3
1DTU Management Engineering, Produktionstorvet Bygning 424.
2DTU Compute, Richard Petersens Plads, bygning 324, DK2800 Kgs. Lyngby.
3Bispebjerg Hospital Dept. of Occupational and Environmental medicine Copenhagen (AMED).

Article ID: 100002O01JH2016
doi:10.5348/O01-2016-2-RA-1

Address correspondence to:
Per Grove Thomsen
DTU Compute, Richard Petersens Plads
bygning 324, DK2800 Kgs. Lyngby

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How to cite this article
Heebøll J, Thomsen PG, Gyntelberg F. Research applications of a coordination ability test system (CATSYS) during 30 years. Edorium J Occup Environ Med 2016;2:1–7.


Abstract
The coordination ability test system (CATSYS) was invented in 1986 with the aim of using it for diagnosing neurological disturbances in people who had been exposed to neurotoxic substances in particular organic solvents. In this brief review, all articles where CATSYS has been used for scientific purposes have been retrieved and read. Articles on neurotoxicity and Parkinson's disease (PD) have been reviewed and referred to. The CATSYS measures hand prono/supination, finger tapping, tremor, reaction time and postural stability. The CATSYS has been used in environmental medicine among people exposed to mercury in food, and in employees exposed occupationally to mercury. Both a decrease in coordination ability and increased tremor has been observed in occupationally exposed groups, but not among people exposed to mercury in food. Similar observations have been seen with regard to manganese exposure where people exposed to manganese from environmental air pollution had no or minor effects in contrast to some occupationally exposed groups. In a few studies on use of alcohol and tobacco a tendency of increased tremor among smokers was observed, and have reduced postural stability among regular users of alcoholic beverages. The CATSYS has been found a useful tool in differential diagnostics between PD and familial essential tremor. CATSYS has been used in many scientific studies globally and has proven its value in research. Potentially, it may be instrumental for clinical purposes in particular in PD.

Keywords: Coordination test, Data acquisition, Environment pollution, Equipment, Neurotoxicology, Organic solvents, Tobacco, Tremor analysis


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Author Contributions
John Heebøll – Substantial contributions to conception and design and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Per Grove Thomsen – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Finn Gyntelberg – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 John Heebøll et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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